Blood tests are a staple diagnostic tool used by modern doctors, allowing physicians to detect and monitor a broad range of health conditions. One of these tests is popularly known as Erythrocyte Sedimentation Rate (ESR): an in vitro test used to determine signs of inflammation in the body. This test is performed using special instruments (ESR tube) that include anticoagulants to ensure the integrity of the blood sample (through a tube).
Why are ESR tube anticoagulants so important in blood tests, and how do they work? In this blog, we are going to discuss about ESR tube anticoagulants, the science behind their use in blood testing, and why they are essential in diagnostic procedures.
Table of Contents
What Is an ESR Test, and Why Is It Important?
TThe Erythrocyte Sedimentation Rate (ESR) test is used to determine how quickly RBCs (red blood cells) settle at the bottom of a test tube in a given period of time. A higher number, which means a faster sedimentation rate, indicates inflammation, which can be the result of infections, autoimmune diseases or chronic diseases.

What is the Procedure for the ESR Test?
- Erythrocyte sedimentation rate (ESR) tube with an anticoagulant is being used to collect a blood sample by a healthcare provider.
- The sample sits vertically for 1 hour.
- Red blood cells settle a certain distance, measured in millimeters (mm/hr) every hour.
- Higher values indicate inflammation or other health problems.
To prevent clotting, 3.8% sodium citrate ESR tubes serve as the best anticoagulant for this purpose.
What Are ESR Tube Anticoagulants and Why Are They Essential?
ESR tube anticoagulants are substances added to vacuum blood collection tubes to prevent clotting and ensure accurate ESR test results. Without these additives, blood would coagulate, making sedimentation measurements impossible.
Why Sodium Citrate Is the Preferred ESR Tube Anticoagulant
The most commonly used anticoagulant for ESR tests is 3.8% sodium citrate, which works by binding calcium ions in the blood, preventing the clotting process.
Key Advantages of 3.8% Sodium Citrate in ESR Tubes:
- Prevents coagulation: Ensures red blood cells remain suspended for accurate sedimentation measurement.
- Maintains stability: Keeps the sample in an optimal condition for testing.
- Minimizes interference: Reduces the risk of inaccurate readings caused by improper anticoagulants.
Explore ESR Tubes with 3.8% Sodium Citrate Here
How Do ESR Tube Anticoagulants Work?
Anticoagulants in ESR tubes play a pivotal role in preserving the blood sample for accurate testing. The most commonly used anticoagulant in ESR tubes is Sodium Citrate (3.8%), which works by binding to calcium ions in the blood. Calcium is a critical component in the clotting process, and by removing it, sodium citrate effectively prevents coagulation.
Here’s how the process works in detail:
- Blood Collection: The anticoagulant immediately contacts the blood when drawn into an ESR tube.
- Calcium Binding: Sodium citrate binds to calcium ions in the blood, preventing the activation of clotting factors.
- Preservation: The anticoagulant maintains the blood in a liquid state, allowing red blood cells to settle naturally during the ESR test.
- Accurate Measurement: The preserved blood sample allows accurate measurement of the sedimentation rate without interference from clotting.
This mechanism ensures that the sample remains viable for testing, even if there is a delay between collection and analysis.
Benefits of Using ESR Tube Anticoagulants
1. Accurate Results:
The use of anticoagulants ensures that the blood remains unclotted, which is essential for obtaining reliable ESR readings.
2. Easy Sample Handling:
Anticoagulated blood is easier to handle and process in the laboratory, reducing the risk of errors.
3. Extended Sample Viability:
Anticoagulants preserve the blood sample for longer periods, making it suitable for delayed testing or transportation to remote laboratories.
4. Standardization:
By maintaining a consistent blood-to-additive ratio, ESR tubes ensure standardized results across different laboratories and testing conditions.
5. Customization Options Available:
OEM/ODM services allow you to customize volume, material, and additive preferences.
Types of ESR Tubes Offered by Siny Medical
At Siny Medical, we offer a range of ESR tubes to meet diverse clinical needs. Our tubes are available in various volumes and materials, including PET and glass.
Volume/ml | Size/mm | Additive | Separator | Material | Cap Color | Closure |
1.6ml / 1.28ml | 8×120 | 3.8% Sodium Citrate | Gel or Not Add | PET/GLASS | Black Top Tube | Safety Cap+Rubber or Rubber Stopper |
2ml | 13X75 | 3.8% Sodium Citrate | ||||
3ml | 13X75 | 3.8% Sodium Citrate | ||||
4ml | 13X75 | 3.8% Sodium Citrate | ||||
5ml | 13X75 | 3.8% Sodium Citrate | ||||
6ml | 13X100 | 3.8% Sodium Citrate | ||||
7ml | 13X100 | 3.8% Sodium Citrate | ||||
8ml | 16X100 | 3.8% Sodium Citrate | ||||
9ml | 16X100 | 3.8% Sodium Citrate | ||||
10ml | 16X100 | 3.8% Sodium Citrate | ||||
If You Need Customized Vacuum Blood collection tube, Please Contact Us |
For a complete list of our products, visit Siny Medical’s ESR Tube Collection.
Why Choose Siny Medical for ESR Tubes?
1. Certified Quality:
Our ESR tubes are CE, ISO13485, and ISO9001 certified, ensuring compliance with international quality standards.
2. Customization Options:
We offer OEM/ODM services to meet specific customer requirements. We provide custom volumes, materials, and additives to meet your needs. Learn more about customization by contacting us at Siny Medical.
3. Sterile and Safe:
We sterilize all our ESR tubes using irradiation to ensure safety and reliability.
4. Free Samples:
We provide free samples to help you evaluate our products before placing bulk orders.
Summary
ESR tube anticoagulants are a critical component in blood testing, ensuring the accuracy and reliability of ESR measurements. By preventing blood clotting, these anticoagulants preserve the sample’s integrity, enabling physicians to diagnose and monitor inflammatory conditions effectively.
At Siny Medical, we pride ourselves on providing high-quality ESR tubes that meet international standards. Whether you’re a distributor, medical chain store, or government procurement agency, we offer a one-stop solution for all your blood collection needs.
For more information about our products and services, visit our ESR tube page or contact us directly at Siny Medical.
FAQ: ESR Tube Anticoagulants
1. What is the purpose of anticoagulants in ESR tubes?
Anticoagulants prevent blood from clotting, ensuring that the sample remains viable for accurate ESR measurement.
2. Why is sodium citrate used in ESR tubes?
Sodium citrate is effective at binding calcium ions, which are essential for blood clotting. Its 3.8% concentration is ideal for preserving blood samples for ESR testing.
3. Can ESR tubes be reused?
ESR tubes are designed for single use only and must be disposed of properly after use to ensure safety and hygiene.
4. Are ESR tubes compatible with all blood collection systems?
Most ESR tubes, including those from Siny Medical, are designed to be compatible with standard blood collection systems.
5. How do I choose the right ESR tube for my needs?
Consider factors such as volume, material (PET or glass), and the presence of a gel separator. For assistance, contact us at Siny Medical.